Tierno, Anthony F.; Walters, Jennifer C.; Vazquez-Lopez, Andres; Xiao, Xiao; Wengryniuk, Sarah E. published the artcile< Heterocyclic group transfer reactions with I(III) N-HVI reagents: access to N-alkyl(heteroaryl)onium salts via olefin aminolactonization>, Formula: C11H16BNO2, the main research area is alkylheteroarylonium salt preparation; alkenoic acid heterocycle aminolactonization.
Herein, leverage (bis)cationic nitrogen-ligated I(III) hypervalent iodine reagents, or N-HVIs, as “”heterocyclic group transfer reagents”” to provide access to a broad scope of N-alkyl(heteroaryl)onium salts e.g., I via the aminolactonization of alkenoic acids e.g., 2,2-diphenylpent-4-enoic acid, the first example of engaging an olefin to directly generate these salts. The reactions proceed in excellent yields, under mild conditions, and are capable of incorporating a broad scope of sterically and electronically diverse aromatic heterocycles such as pyridine, 4-piperidinylpyridine, 1-methylimidazole, etc.. The N-HVI reagents can be generated in situ, the products are isolated via simple trituration, and subsequent derivatizations demonstrate the power of this platform for diversity-oriented synthesis of 6-membered nitrogen heterocycles e.g., I.
Chemical Science published new progress about Amination. 329214-79-1 belongs to class pyridine-derivatives, and the molecular formula is C11H16BNO2, Formula: C11H16BNO2.