Leibler, Isabelle Nathalie-Marie; Tekle-Smith, Makeda A.; Doyle, Abigail G. published the artcile< A general strategy for C(sp3)-H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor>, Recommanded Product: Ir(p-F-ppy)3, the main research area is hydrocarbon triethylamine hydrogen fluoride iridium catalyst photochem fluorination reaction; hydrofluorocarbon preparation; difluorodiphenylmethane nucleophile iridium catalyst photochem carbon hydrogen functionalization; carbon functionalized difluorodiphenylmethane preparation.
A strategy that transforms C(sp3)-H bonds into carbocations via sequential hydrogen atom transfer (HAT) and oxidative radical-polar crossover were discussed. The resulting carbocation was functionalized by a variety of nucleophiles-including halides, water, alcs., thiols, an electron-rich arene and an azide-to effect diverse bond formations. Mechanistic studies indicated that HAT was mediated by Me radical-a previously unexplored HAT agent with differing polarity to many of those used in photoredox catalysis-enabling new site-selectivity for late-stage C(sp3)-H functionalization.
Nature Communications published new progress about Bond activation catalysts. 370878-69-6 belongs to class pyridine-derivatives, and the molecular formula is C33H21F3IrN3, Recommanded Product: Ir(p-F-ppy)3.