Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 13603-44-6, name is 2,6-Dimethylpyridin-4-ol. This compound has unique chemical properties. The synthetic route is as follows. Formula: C7H9NO
2,6-Dimethyl-pyridin-4-yl trifluoromethanesulfonate (91)A suspension of pyridone 90 (5.0 g, 40.6 mmol) in DCM (100 mL) at 0C is treated with triethylamine (8.50 mL, 60.9 mmol) followed by trifluoromethane-sulfonic anhydride (10.2 mL, 60.9 mmol), added dropwise via syringe over 5 minutes. After warming to RT and stirring 2 h, the reaction mixture is washed with aqueous NaHCO3 (3 x 100 mL) and reduced in vacuo to afford the title compound. Yield: 9.25 g (quant.). LC/MS U 0.96 min. MS(ES+) m/z 256 (M+H).
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Reference:
Patent; CURIS, INC.; WO2008/57497; (2008); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem