《Design, synthesis, and evaluation of anticancer potential of some new benzopyran Schiff base derivatives》 was published in Indian Journal of Heterocyclic Chemistry in 2020. These research results belong to Kumar, Piyush; Rahman, Azizur Md.; Wal, Pranay; Singh, Kuldeep. Name: 4-Acetylpyridine The article mentions the following:
The present study was carried out to design, synthesize, and evaluate the anticancer activity of newly synthesized benzopyran Schiff bases I [R1 = Me, R2 = Ph, 4-ClC6H4, 2-pyridyl, etc.; R1 = R2 = Ph; R1R2C = adamantan-2-ylidene] on MCF-7 and MDA-MB-231 cell lines. Docking studies, in silico absorption, distribution, metabolism, elimination (ADME), and predicted toxicity studies have also been performed. Designed compounds I were synthesized by condensation of the substituted Trolox hydrazide with various ketones. All synthesized compounds I were tested on MCF-7 and MDA-MB-231 cell lines for anticancer activity. All compounds I, except for I (R1 = Me; R2 = 2-naphthyl) showed better docking scores than standard The majority of the compounds displayed good to potent anticancer activity on MCF-7 and MDA-MB-231 cell lines. After reading the article, we found that the author used 4-Acetylpyridine(cas: 1122-54-9Name: 4-Acetylpyridine)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Name: 4-Acetylpyridine