Zhang, Qun-Liang; Yu, Qin-qin; Ma, Li; Lu, Xuelian; Fan, Qing-Tian; Duan, Tian-Shun; Zhou, Yirong; Zhang, Fang-Lin published the artcile< A Metal-Free Visible-Light Photoredox Construction and Direct C-H Functionalization of Pyridines: Green Synthesis of Polysubstituted Picolinaldehydes>, COA of Formula: C6H4F3N, the main research area is picolinaldehyde preparation green chem; pyridine metal free visible light electrocyclization tandem Minisci reaction.
The development of a novel environmental benign and sustainable synthetic method for highly efficient construction and direct C-H functionalization of N-heterocycles remains a pivotal central research topic for organic and medicinal chem. Herein, a novel visible-light-enabled biomimetic aza-6π electrocyclization for efficient assembly of diverse pyridines and further tandem Minisci-type reaction were developed. A broad spectrum of polysubstituted picolinaldehydes were readily constructed with high efficacy and good functional group tolerance under metal- and oxidant-free conditions.
Journal of Organic Chemistry published new progress about Cyclization, electrophilic. 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, COA of Formula: C6H4F3N.