Related Products of 67443-38-3, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.67443-38-3, name is 5-Bromo-2-chloro-3-nitropyridine, molecular formula is C5H2BrClN2O2, molecular weight is 237.44, as common compound, the synthetic route is as follows.
Compound A (30.0 g), glycine-tert-butyl ester hydrochloride(23.3 g) and DMA (250 mL) was added triethylamine(38.4 mL) was added dropwise at 50 C. After completion of the dropwise addition,Followed by stirring at 50 C. for 2 hours. To the reaction mixture was added toluene (400 mL)And the mixture was washed with water, 1% hydrochloric acid and water in this order. After drying over sodium sulfate,A toluene solution of compound B was obtained.
Statistics shows that 67443-38-3 is playing an increasingly important role. we look forward to future research findings about 5-Bromo-2-chloro-3-nitropyridine.
Reference:
Patent; SUMITOMO DAINIPPON PHARMA COMPANY LIMITED; LEE, SHOUKOU; IWAMOTO, KOHEI; (57 pag.)JP2016/132649; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem