Reference of 3-Nitroisonicotinic acidOn September 30, 1991 ,《Proton, carbon-13 and oxygen-17 NMR study of substituted nitropyridines》 was published in Magnetic Resonance in Chemistry. The article was written by Kolehmainen, Erkki; Laihia, Katri; Rasala, Danuta; Gawinecki, Ryszard. The article contains the following contents:
1H, 13C and 17O NMR spectra for 22 substituted nitropyridines were measured and their 1H NMR spectra were analyzed. The most significant variations in the NMR parameters are found for isomeric hydroxy derivatives, owing to the possibility of keto-enol tautomerism. The prevalence of the keto form is observed in 2- and 4-hydroxy derivatives, while the 3-hydroxy derivative exists in its enol form. Among the three nuclei studied, 17O seems to be the best nucleus for probing the keto-enol tautomerism. No correlation is observed between the torsion angle of the nitro group and its 17O NMR chem. shift. Mol. mechanics calculations were performed to clarify the torsional energetics of the nitro group and the preferences for keto-enol tautomerism. In addition to this study using 3-Nitroisonicotinic acid, there are many other studies that have used 3-Nitroisonicotinic acid(cas: 59290-82-3Reference of 3-Nitroisonicotinic acid) was used in this study.
3-Nitroisonicotinic acid(cas: 59290-82-3) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Reference of 3-Nitroisonicotinic acid