Category: pyridine-derivativesIn 2021 ,《On-Surface Synthesis of Giant Conjugated Macrocycles》 was published in Angewandte Chemie, International Edition. The article was written by Fan, Cunrui; Sun, Bangjin; Li, Zhanbo; Shi, Jiwei; Lin, Tao; Fan, Jian; Shi, Ziliang. The article contains the following contents:
We have achieved an on-surface synthesis of giant conjugated macrocycles having a diameter of ≈7 nm and consisting of up to 30 subunits. The synthesis started with a debrominative coupling of the mol. precursors on a hot Ag(111) surface, leading to the formation of arched oligomeric chains and macrocycles. These products were revealed by scanning tunneling microscopy in combination with d. functional theory to be covalent oligomers. These intermediates also display C-Ag organometallic bonds between parallel mol. subunits due to site-selective debromination and the asym. mol. conformation. Subsequent cyclodehydrogenation at higher temperatures steered the final conjugation of the macrocycles. Our findings provide a novel design strategy toward π-conjugated macrocycles and open up new opportunities for the precise synthesis of organic nanostructures. The results came from multiple reactions, including the reaction of 2,6-Dibromopyridine(cas: 626-05-1Category: pyridine-derivatives)
2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Category: pyridine-derivatives