Related Products of 1692-25-7In 2021 ,《Catalytic Enantioselective Synthesis of Pyridyl Sulfoximines》 appeared in Journal of the American Chemical Society. The author of the article were Tang, Yu; Miller, Scott J.. The article conveys some information:
The synthesis of chiral sulfoximines, e.g., I, through the desymmetrizing N-oxidation of pyridyl sulfoximines, e.g., II, using an aspartic-acid-containing peptide catalyst III (R = Ts, Boc) was reported. Various mono- and bis-pyridyl sulfoximine oxides, e.g., I and IV, are obtained with up to 99:1 er. The directing group introduced on the substrate highly enhances the enantioinduction and could be easily removed to give the free N-H sulfoximines V. Addnl., peptides with Me ester and the Me amide C-terminal protecting group give the opposite enantiomers of the product. A binding model is proposed to explain this phenomenon. The experimental process involved the reaction of Pyridin-3-ylboronic acid(cas: 1692-25-7Related Products of 1692-25-7)
Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Related Products of 1692-25-7