Shvydkiy, Nikita V.; Vyhivskyi, Oleksandr; Nelyubina, Yulia V.; Perekalin, Dmitry S. published the artcile< Design of Manganese Phenol Pi-complexes as Shvo-type Catalysts for Transfer Hydrogenation of Ketones>, Formula: C7H7NO, the main research area is manganese phenol pi complex preparation; secondary alc preparation; ketone transfer hydrogenation manganese complex catalyst.
The ability of the manganese pi-complexes to act as Shvo-type catalysts for transfer hydrogenation of ketones to afford secondary alcs. RCH(OH)(R1) [R = Ph, 3-pyridyl, 1-naphthyl, etc.; R1 = Me, n-Pr, Ph, etc.] was explored. DFT calculations suggested that the transfer of hydrogen atoms from the hypothetical intermediate [(C6Me3H2OH)Mn(CO)2H] to acetone had low activation barrier of 10.9 kcal mol-1. Exptl. a number of ketones with various functional groups were successfully reduced in isopropanol in the presence of the complex [(C6Me3H2OH)Mn(CO)3]BF4 (1 mol %) and tBuOK (75 mol %). However, further investigation revealed that the reduction was mainly promoted by base rather than the manganese complex.
ChemCatChem published new progress about Ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.