Related Products of 103-74-2In 2018 ,《Solid-Phase Synthesis of Tetramic Acid via Resin-Bound Enol Ethers as a Privileged Scaffold in Drug Discovery》 was published in Advanced Synthesis & Catalysis. The article was written by Schuetznerova, Eva; Oliver, Allen G.; Pribylka, Adam; Krchnak, Viktor. The article contains the following contents:
This paper reports the practical synthesis of a tetramic acid scaffold on solid phase using simple, com. available building blocks under mild conditions. Acyclic precursors were assembled on solid phase in four steps, and cyclization was achieved by Wittig olefination. The target compounds contained three points of diversification and allowed for further modifications while still being attached to the resin. Solid-phase synthesis represents a method of choice, particularly for parallel synthesis, because the intermediates can be isolated simply and quickly by washing the resin beads, which typically takes only minutes.2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Related Products of 103-74-2) was used in this study.
2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Related Products of 103-74-2