The author of 《Bioactive NHC-derived palladium complexes: synthesis, catalytic activity for the Suzuki-Miyaura coupling of aryl chlorides and bromides and their antibacterial activities》 were Boubakri, Lamia; Al-Ayed, Abdullah S.; Mansour, L.; Abutaha, Nael; Harrath, Abdel Halim; Ozdemir, I.; Yasar, S.; Hamdi, Naceur. And the article was published in Journal of Coordination Chemistry in 2019. Product Details of 626-05-1 The author mentioned the following in the article:
Pd(II)-bis(NHC) complexes (NHC = N-heterocyclic carbene) bearing asym. and sym. substituted NHC-ligand were synthesized via deprotonation of 5,6-dimethylbenzimidazolium salts. The NHC precursors were achieved via the two step N-alkylation of 5,6-dimethylbenzimidazole. The resultant salts were deprotonated with PdCl2 and K2CO3 in dry THF for (2a-2e). The obtained complexes were identified and characterized by 1H and 13C NMR, FTIR, DART-TOF mass spectrometry and elemental anal. These new Pd(II)-bis(NHC) complexes were applied as catalyst precursors for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides with phenylboronic acid to afford the corresponding products in good yields. This catalytic reaction was evaluated in the presence of KOtBu/toluene. The antibacterial activities of (2a-2e) were studied against Gram (+)/(-) bacteria using the agar dilution procedure. The antibacterial activities of 2 vary with the nature of the ligands; MIC values of (2a-2e) were determined The results came from multiple reactions, including the reaction of 2,6-Dibromopyridine(cas: 626-05-1Product Details of 626-05-1)
2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Product Details of 626-05-1