Pratap, Ramendra; Yorimitsu, Hideki published the artcile< Palladium-Catalyzed Amination of Aryl Sulfides and Sulfoxides with Azaarylamines of Poor Nucleophilicity>, Recommanded Product: N-Phenylpyridin-4-amine, the main research area is heteroaryl amine preparation; sulfide aryl azaarylamine amination palladium catalyst; sulfoxide aryl azaarylamine amination palladium catalyst.
The amination of aryl sulfides and sulfoxides (Ar)2S and (Ar)2SO2 [Ar = C6H5, 2-naphthyl, biphenyl-4-yl, etc.] with azaarylamines R1NH2 (R1 = pyrimidin-2-yl, pyrazin-2-yl, quinolin-3-yl, etc.) is investigated using a palladium-N-heterocyclic carbene (NHC) complex I. Because azaarylamines are less nucleophilic than anilines, more reactive diaryl sulfides and sulfoxides are found to be suitable coupling partners that liberate better leaving arenethiolate or arenesulfenate anions, instead of aryl Me sulfides RSCH3 [R = 4-FC6H4, 2-naphthyl, 4-(2,5,5-trimethyl-1,3-dioxan-2-yl)phenyl, etc.] as reported previously.
Synthesis published new progress about Amination. 22961-45-1 belongs to class pyridine-derivatives, and the molecular formula is C11H10N2, Recommanded Product: N-Phenylpyridin-4-amine.