《Experimental, quantum computational study and in vitro antidiabetic activity of oxidovanadium(IV) complexes incorporating 2,2′-bis(pyridylmethyl)amine and polypyridyl ligands》 was written by Patel, Neetu; Prajapati, A. K.; Jadeja, R. N.; Tripathi, I. P.; Dwivedi, N.. Computed Properties of C12H13N3This research focused onvanadyl pyridylmethyl amine diimine complex preparation DFT calculation; magnetic property cyclic voltammetry vanadyl pyridylmethyl amine diimine complex; antidiabetic activity vanadyl pyridylmethyl amine diimine complex. The article conveys some information:
This article describes synthesis and characterization of three oxidovanadium(IV) complexes using BPA (BPA = 2,2′-bis(pyridylmethyl)amine), 2,2-bipyridyl and 1,10-phenanthroline. These complexes were characterized by elemental anal., spectroscopic (UV-visible, IR and EPR) and electrochem. methods. Room temperature magnetic susceptibility data show the paramagnetic nature of the complexes. Complexes were also characterized by EPR spectral techniques. The optimized mol. structures show N3O3/N5O donor atoms in six-coordinate geometry. These complexes were evaluated and compared using TGA and powder x-ray diffraction techniques. The species exhibit only one-electron reduction wave at a more neg. potential. The catalytic activity of these complexes was also explored to mimic α-glucosidase and α-amylase activity. Moderate α-glucosidase and α-amylase inhibitors are shown by all complexes. These observations are expected to expand the possibility of designing new oxidovanadium(IV) complexes with significant anti-diabetic properties. In addition to this study using Bis(pyridin-2-ylmethyl)amine, there are many other studies that have used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Computed Properties of C12H13N3) was used in this study.
Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Computed Properties of C12H13N3