The author of 《Logic gate behavior and intracellular application of a fluorescent molecular switch for the detection of Fe3+ and cascade sensing of F- in pure aqueous media》 were Dwivedi, Romi; Singh, Divya P.; Singh, Saumya; Singh, Ashish K.; Chauhan, Brijesh S.; Srikrishna, S.; Singh, Vinod P.. And the article was published in Organic & Biomolecular Chemistry in 2019. Electric Literature of C5H7N3 The author mentioned the following in the article:
The nature and coordination sites of the Schiff base 3,3′-(1E,1′E)-(1,3-phenylenebis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene)dinaphthalen-2-ol (APHN) were tuned by its selective reduction to design a highly efficient fluorescent probe, 3,3′-(pyridine-2,6-diylbis(azanediyl))bis(methylene)dinaphthalen-2-ol (RAPHN). The structures of APHN, RAPHN, and the RAPHN-Fe3+ complex were satisfactorily modeled from the results of d. functional theory (DFT) and time-dependent DFT (TD-DFT) calculations RAPHN worked in pure aqueous medium as a turn on-off-on probe of Fe3+ and F-. The fluorescence nature of the probe in the presence and absence of Fe3+/F- was regulated by a set of mechanisms including -CH=N isomerization and LMCT. A 2 : 1 (M : L) binding stoichiometry was established from a fluorescence Job′s plot and further substantiated from HR-MS studies. The limits of detection of RAPHN for Fe3+ and RAPHN-Fe3+ for F- were found to be 2.49 × 10-7 M and 1.09 × 10-7 M, resp. The RAPHN probe caused no cytotoxicity in gut tissue of Drosophila even at high concentrations The probe displayed excellent bioimaging applications for detection of Fe3+ and F- in gut tissue of Drosophila. A combinatorial logic gate was constructed for the proper understanding of the working principle of RAPHN. In the experiment, the researchers used 2,6-Diaminopyridine(cas: 141-86-6Electric Literature of C5H7N3)
2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Electric Literature of C5H7N3