SDS of cas: 828918-24-7On June 7, 2019, Sattar, Moh.; Patidar, Krishna; Thorat, Raviraj Ananda; Kumar, Sangit published an article in Journal of Organic Chemistry. The article was 《Copper-Mediated Selective Mono- and Sequential Organochalcogenation of C-H Bonds: Synthesis of Hybrid Unsymmetrical Aryl Ferrocene Chalcogenides》. The article mentions the following:
A 8-aminoquinoline directed Cu/1,10-phenanthroline-mediated selective mono-organothiolation of C-H bond in ferroceneamide was developed using aryl/alkyl-disulfide substrates. The sequential ferrocene C-H organochalcogenation (chalcogen = S, Se, and Te) also was established for the synthesis of novel hybrid unsym. aryl chalcogenides with the aid of a catalytic amount of Cu(OAc)2 under ambient reaction conditions. The developed protocol exhibits a broad functional group tolerance to allow alkyl, aryl, hetero-aryl, bromo, chloro, and nitro containing diorgano dichalcogenides as a coupling partner. Further, the 8-aminoquinoline directing group is easily removed to afford the aldehyde functionality after C-H organochalcogenation. A mechanistic understanding of the Cu-mediated selective mono-organothiolation reaction suggests that rigid bi-coordinated 1,10-phenanthroline ligand and freshly generated Cu(II) from Cu(I) in the less polar solvent MeCN seem crucial for the selective mono-C-H functionalization of ferroceneamide. In the experiment, the researchers used many compounds, for example, 2,6-Bis((R)-4-isopropyl-5,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine(cas: 828918-24-7SDS of cas: 828918-24-7)
2,6-Bis((R)-4-isopropyl-5,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine(cas: 828918-24-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. SDS of cas: 828918-24-7 Pyridine has a conjugated system of six π electrons that are delocalized over the ring.