《In Situ Ring-Closing Strategy for Direct Synthesis of N-Heterocyclic Carbene Nickel Complexes and Their Application in Coupling of Allylic Alcohols with Aryl Boronic Acids》 was published in Advanced Synthesis & Catalysis in 2020. These research results belong to Wang, Yu-Bin; Liu, Bin-Yuan; Bu, Qingqing; Dai, Bin; Liu, Ning. Synthetic Route of C5H3Br2N The article mentions the following:
An in situ ring-closing strategy was developed for the synthesis of N-heterocyclic carbene nickel complexes, e.g., I. The process was carried out in air, and did not require solvent purification The resulting nickel complexes were investigated as catalysts for the coupling of allylic alcs. RCH=CHCH(OH)R1 (R = H, Me, phenyl; R1 = Me, Ph, thiophen-3-yl, etc.) with aryl boronic acids R2B(OH)2 (R2 = 4-methoxyphenyl, thiophen-3-yl, naphthalen-2-yl, etc.). A wide range of allylic substrates and aryl acids proved to be applicable to this catalytic system. Control experiments suggest that the Ni(0) may be the true active species in the coupling reactions. The results came from multiple reactions, including the reaction of 2,6-Dibromopyridine(cas: 626-05-1Synthetic Route of C5H3Br2N)
2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Synthetic Route of C5H3Br2N