Safety of Methyl 5-bromopicolinateIn 2016 ,《A Convenient Process for the Preparation of Heteroaryl Trifluoromethyl Selenoethers》 was published in Chinese Journal of Chemistry. The article was written by Tian, Qinli; Weng, Zhiqiang. The article contains the following contents:
The preparation of heteroaryl trifluoromethyl selenoethers RSeCF3 (R = 3-methoxypyridin-5-yl, imidazo[1,2-a]pyrazin-6-yl, 6-methoxybenzo[d]thiazol-2-yl, etc.) by the trifluoromethylselenolation of heteroaryl bromides RBr with [(bpy)CuSeCF3]2 was investigated. A large number of trifluoromethylselenolated heterocyclic compounds were synthesized in good to excellent yields using this approach. It was demonstrated that this procedure tolerates a wide variety of functional groups. In the experiment, the researchers used many compounds, for example, Methyl 5-bromopicolinate(cas: 29682-15-3Safety of Methyl 5-bromopicolinate)
Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Safety of Methyl 5-bromopicolinate