Recommanded Product: 128071-75-0In 2021 ,《Microwave accelerated Castagnoli-Cushman reaction: Synthesis of novel 6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazines》 was published in Tetrahedron Letters. The article was written by Vytla, Devaiah; Shaw, Parinita; Velayuthaperumal, Rajeswari; Emmadi, Jithendra; Mathur, Arvind; Roy, Amrita. The article contains the following contents:
The Castagnoli-Cushman reaction of various azaindole dicarboxylic acids with imines using acetic anhydride as a dehydrating agent was significantly accelerated by microwave irradiation The reaction conditions offered a convenient preparation of novel 6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazines I [R1 = H, MeO, Cl, X = CH, N; Y = CH, N; Z = CH, N; R2 = 4-MeC6H4, 3-FC6H4, 4-MeOC6H4, 4-NO2C6H4, 2-thienyl; R3 = n-Pr, cyclopropyl, 4-MeC6H4, etc.] in moderate to good yields with good trans stereoselectivity. In the experiment, the researchers used many compounds, for example, 2-Bromonicotinaldehyde(cas: 128071-75-0Recommanded Product: 128071-75-0)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Recommanded Product: 128071-75-0