In 2022,Arbour, Christine A.; Imperiali, Barbara published an article in Organic Letters. The title of the article was 《Backbone-anchoring, solid-phase synthesis strategy to access a library of peptidouridine-containing small molecules》.HPLC of Formula: 2510-22-7 The author mentioned the following in the article:
Nucleoside diphosphate sugar (NDP-sugar) substrates provide the inspiration for nucleoside analog inhibitor scaffolds. By employing solid-phase synthesis, we provide a method to access a library of peptidouridine inhibitors with both minimal compound handling and purification steps. Specifically, this strategy is exemplified by generating uridine diphosphate sugar (UDP-sugar) mimics, which allow for compound elaboration by altering the dipeptide composition, the N-terminal linkage, and a pendant aryl group. To exemplify the versatility, 41 unique nucleoside analogs are presented. The experimental process involved the reaction of 4-Ethynylpyridine(cas: 2510-22-7HPLC of Formula: 2510-22-7)
4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. HPLC of Formula: 2510-22-7