《Synthesis of perfluoroalkylated bipyridines – new ligands for oxidation reactions under fluorous triphasic conditions》 was written by Quici, Silvio; Cavazzini, Marco; Ceragioli, Silvia; Montanari, Fernando; Pozzi, Gianluca. Application In Synthesis of 4,4′-Bis(chloromethyl)-2,2′-bipyridine And the article was included in Tetrahedron Letters on April 30 ,1999. The article conveys some information:
Fluorous soluble bipyridines bearing two perfluoroalkylated side chains in the 6,6′- or 4,4′-positions have been prepared in good yields via etherification of 6,6′-bis(chloromethyl)-2,2′-bipyridine or C-alkylation of 4,4′-dimethyl-2,2′-bipyridine. The new ligands L exhibit amphiphilic behavior with respect to certain fluorous-organic biphasic systems. Nevertheless, their ruthenium complexes (RuLn)X generated in situ are efficient catalysts for the epoxidation of trans-stilbene in a fluorous triphasic system CH2Cl2/H2O/C8F18 in the presence of NaIO4. The fluorous phase, where (RuLn)X is trapped, can be used up to four times without major loss of catalytic activity. In addition to this study using 4,4′-Bis(chloromethyl)-2,2′-bipyridine, there are many other studies that have used 4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4Application In Synthesis of 4,4′-Bis(chloromethyl)-2,2′-bipyridine) was used in this study.
4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. Application In Synthesis of 4,4′-Bis(chloromethyl)-2,2′-bipyridine Pyridine has a conjugated system of six π electrons that are delocalized over the ring.