The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5345-47-1, name is 2-Aminonicotinic acid. This compound has unique chemical properties. The synthetic route is as follows. HPLC of Formula: C6H6N2O2
Equipped with a blender,Reflux condenser 500mL three-necked flask,20.7 g (0.15 mol) of 2-aminonicotinic acid,80 mL acetic acid,Stirred at room temperature,A constant pressure dropping funnel was added dropwise with a mixed solution of 40 mL of acetic acid and 4.1 mL of bromine (0.08 mol)Drop end to continue mixing 4-5h.filter,Washed with acetic acid,dry,The solid was refluxed with methanol 100mL 10min 10min at room temperature,Filter and dry.31.2g of white solid was obtained,Yield 96%.
With the rapid development of chemical substances, we look forward to future research findings about 5345-47-1.
Reference:
Patent; Southern Medical University; Wan Shanhe; Wang Guangfa; Wu Xiaoyun; Tian Yuanxin; Ye Ling; Li Zhonghuang; Zhang Tingting; Zhu Zhengguang; Jin Hong; Zhang Jiajie; (27 pag.)CN106565684; (2017); A;,
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