Application In Synthesis of Bis(pyridin-2-ylmethyl)amineIn 2020 ,《A cyclometalated trinuclear Ir(III)/Pt(II) complex as a luminescent probe for histidine-rich proteins》 appeared in Dalton Transactions. The author of the article were Sarkar, Ankita; Kumar, Ravi; Das, Bishnu; Ray, Partho Sarothi; Gupta, Parna. The article conveys some information:
Organometallic complexes have important application in the field of protein staining, with potential for use in proteomic anal. The rational synthesis of a trinuclear luminescent organometallic complex with two platinum(II) centers appended to the cyclometalated ligand of the iridium(III) center is reported here. Two di-2-picolylamine groups bonded to the cyclometalated Ph pyridine moiety provide three coordinating sites to each platinum center. The replacement of chloride in the fourth coordination site of two square planar platinum metal centers with the imidazole nitrogen or sulfur atom of histidine/cysteine is evident from the change in luminescence intensity upon binding these amino acids. The increase in luminescence emission intensity upon binding of histidine to the organometallic complex allowed it to be used as a protein staining agent. Reversibility of staining upon washing with imidazole enhances the possibility of its application in mass spectrometric anal. The experimental process involved the reaction of Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Application In Synthesis of Bis(pyridin-2-ylmethyl)amine)
Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Application In Synthesis of Bis(pyridin-2-ylmethyl)amine