《Photocatalytic Radical Aroylation of Unactivated Alkenes: Pathway to β-Functionalized 1,4-, 1,6-, and 1,7-Diketones》 was written by Sarkar, Satavisha; Banerjee, Arghya; Yao, Wang; Patterson, Eric V.; Ngai, Ming-Yu. Computed Properties of C33H24IrN3This research focused onunsym diketone preparation photoredox catalysis; aroyl chloride unactivated alkene aroylation photochem; 1,n-diketones; aroylation; migration; photoredox catalysis; unactivated alkenes. The article conveys some information:
The development of a photocatalytic strategy for the synthesis of β-functionalized unsym. 1,4-, 1,6-, and 1,7-diketones from aroyl chlorides and unactivated alkenes at room temperature is reported. The mild reaction conditions not only tolerate a wide range of functional groups and structural moieties, but also enable migration of a variety of distal groups including (hetero)arenes, nitrile, aldehyde, oxime derivative, and alkene. The efficiency of chirality transfer, factors that control the distal-group migration, and synthesis of carbocycles and heterocycles from the diketones are also described. Mechanistic studies suggest a reaction pathway involving a photocatalytic radical aroylation of unactivated alkenes followed by a distal-group migration, oxidation, and deprotonation to afford the desired diketones. The experimental process involved the reaction of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Computed Properties of C33H24IrN3)
fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Computed Properties of C33H24IrN3