Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Name: 5-Bromo-2-fluoropyridine.
Kosobokov, Mikhail;Cui, Benqiang;Balia, Andrii;Matsuzaki, Kohei;Tokunaga, Etsuko;Saito, Norimichi;Shibata, Norio research published 《 Importance of a Fluorine Substituent for the Preparation of meta- and para-Pentafluoro-λ6-sulfanyl-Substituted Pyridines》, the research content is summarized as follows. 3- And 4-(Pentafluorosulfanyl)pyridines are prepared by oxidative chlorotetrafluorination of the corresponding disulfides to give pyridylsulfur chlorotetrafluorides (SF4Cl-pyridines), followed by chloride/fluoride exchange with fluorides; the presence of at least one fluoro substituent on the pyridine rings is necessary for the oxidative chlorotetrafluorination of the pyridinyl disulfides. A variety of 3- and 4-pentafluorosulfanyl pyridines were prepared; pentafluorosulfanylpyridines with 2- or 6-fluoro substituents underwent nucleophilic substitution reactions with benzyl alc., benzylamine, benzylthiol, ammonia, sodium azide, and trimethylsilyl cyanide to yield 3- or 4-pentafluorosulfanyl pyridines with cyano, amino, alkoxy, or azido substituents. This method provides access to a variety of previously unavailable SF5-substituted pyridine building blocks.
766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , Name: 5-Bromo-2-fluoropyridine