On November 9, 2006, Kelly, Michael G.; Kincaid, John; Kaub, Carl J. published a patent.Related Products of 39919-70-5 The title of the patent was Preparation of fused heterocyclic compounds for preventing and treating various diseases. And the patent contained the following:
The title compounds I [A, B = (un)substituted CH2, CO or CS; Y = (un)substituted CH2; W = CR4, N; Z = O, NR2; L = (hetero)alkylene; R1 = carbocyclyl or heterocyclyl; R2 = H, alkyl, cycloalkyl; R3 = carbocyclyl or heterocyclyl; R4 = H, alkyl, acyl, etc.; R5 = R4, Z’-L’-R4 (wherein Z’ = a bond, O, S, etc.; L’ = alkylene)], useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others, were prepared and formulated. E.g., a multi-step synthesis of II, starting from Et 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride, was given. The exemplified compounds I were tested in calcium uptake assay (P2X2 and P2X3) and % inhibition data were given for representative compounds I. The experimental process involved the reaction of 6-(tert-Butyl)pyridin-3-amine(cas: 39919-70-5).Related Products of 39919-70-5
The Article related to fused heterocycle pyridopyrimidinamine preparation purinoceptor antagonist analgesic antiinflammatory anxiolytic, cognition enhancer pyridopyrimidinamine preparation purinoceptor antagonist, antidepressant pyridopyrimidinamine preparation purinoceptor antagonist and other aspects.Related Products of 39919-70-5