Electric Literature of 1594-57-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1594-57-6, name is N-Hydroxyisonicotinimidamide. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To a solution of 0.51 g 3-fluoro-4-methoxybenzoic acid (2,3 mmol) in 10 cm3 of DMF 1.15 g 1-[bis(dimethylamino)methylene]-1H-[1,2,3]-triazolo[4,5-b]pyridinium-3-oxide hexafluorophosphate (HATU, 3 mmol) was addedfollowed by 1 cm3 N-methylmorpholine (9 mmol) andlastly substituted aryl amidoximes 1a-1f in DMF. Thereaction mixture was stirred and refluxed for 3 h. Afterremoval of solvent under vacuum, the reaction mixture waspurified on a silica gel column eluting with 1-5 %methanol in dichloromethane. The desired 3,5-disubstituted1,2,4-oxadiazoles were isolated and crystallized from ethanol.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1594-57-6, N-Hydroxyisonicotinimidamide.
Reference:
Article; Dinesha; Viveka, Shivapura; Khandige, Prasanna S.; Nagaraja, Gundibasappa K.; Monatshefte fur Chemie; vol. 147; 2; (2016); p. 435 – 443;,
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