Pyridine is colorless, but older or impure samples can appear yellow. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Safety of Pyridine-3-sulfonyl chloride.
Luo, Xu;Wang, Shengchun;Lei, Aiwen research published 《 Electrochemical-Induced Hydroxysulfonylation of α-CF3 Alkenes to Access Tertiary β-Hydroxysulfones》, the research content is summarized as follows. An electrochem. hydroxysulfonylation of α-CF3 alkenes RC(=CH2)CF3 (R = 4-CH3OC6H4, 2,3-dihydro-1,4-benzodioxin-6-yl, naphthalen-2-yl, etc.) was accomplished in this work. By using easily available sodium sulfinates R1SO2Na (R1 = Me, Ph, cyclopropyl, etc.) as the sulfonylating agents, a series of valuable α-trifluoromethyl tertiary alcs. RC(OH)CF3CH2S(O)2R1 was synthesized under mild and environmentally friendly electrolysis conditions in moderate to good yields. The preliminary mechanistic investigation indicates that this difunctional reaction involves a radical process via a sulfonyl radical. Gram-scale synthesis shows the significant potential application of this protocol.
Safety of Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.