The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 83004-10-8, name is 2-Bromo-6-(bromomethyl)pyridine. This compound has unique chemical properties. The synthetic route is as follows. Formula: C6H5Br2N
Potassium hydride (105 mg) is added to an ice-cooled mixture of S,S- dimethylsulfoximine (34 mg) and tetrabutylammonium bromide (6 mg) in tetrahydrofuran (2 ml_) under an argon atmosphere and the resulting mixture is stirred at 0C for 1 h. 2-Bromo-6-bromomethyl-pyridine (101 mg) is added, the mixture is allowed to warmed to room temperature overnight and quenched with water. The organic phase washed with brine, dried over MgS04, and concentrated in vacuo. The residue is chromatographed on silica gel (dichloromethane/methanol acetate 99:1?90:10) to give the title compound. LC (method 1 ): tR = 0.62 min; Mass spectrum (ESI+): m/z = 264, 266 [M+H]+
With the rapid development of chemical substances, we look forward to future research findings about 83004-10-8.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; HIMMELSBACH, Frank; LANGKOPF, Elke; WAGNER, Holger; WO2015/7669; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem