Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. HPLC of Formula: 31181-90-5.
Ramaiah, Manjunatha M.;Shivananju, Nanjunda Swamy;Shubha, Priya Babu research published 《 A Facile, Efficient and Solvent-Free Titanium (IV) Ethoxide Catalysed Knoevenagel Condensation of Aldehydes and Active Methylenes》, the research content is summarized as follows. A convenient method was illustrated for the preparation of α,β-unsaturated compounds using both conventional and microwave irradiation methods. An efficient and solvent free Knoevenagel condensation between aldehydes and active methylenes was developed using titanium ethoxide. The procedure proved to be successful with a wide range of substrates such as aromatic, aliphatic and heterocyclic aldehydes and various active methylenes to afford substituted olefins. The reaction was also carried out under microwave irradiation to accomplish the corresponding olefins with improved reaction rates, yields and cleaner reaction profiles. An efficient and novel methodol. was developed for the synthesis of olefinic compounds by Knoevenagel condensation under solvent-free conditions using titanium ethoxide, for the first time, as a reagent as well as a solvent. The significant advantages offered by this methodol. could be applied to various active methylenes in order to offer the corresponding Knoevenagel products. Thus, we believed that this method delivers high conversions, cleaner reaction profiles under solvent-free reaction conditions and shorter reaction times, all of which make it a very useful and attractive approach for the preparation of a wide range of substituted olefins.
31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.
5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., HPLC of Formula: 31181-90-5