Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Recommanded Product: 2-Bromo-6-methylpyridine.
Wu, Zeng-Hua;Cheng, An-Qi;Yuan, Meng;Zhao, Ya-Xuan;Yang, Huai-Lan;Wei, Li-Hua;Wang, Huai-Yu;Wang, Tao;Zhang, Zunting;Duan, Wei-Liang research published 《 Cobalt-Catalysed Asymmetric Addition and Alkylation of Secondary Phosphine Oxides for the Synthesis of P-Stereogenic Compounds》, the research content is summarized as follows. Secondary pyridyl arylphosphine oxides undergo addition to activated double bonds and nucleophilic substitution with benzyl halides catalyzed by cobalt(II) complexes with chiral pincer isoindole-bis(oxazoline) ligands yielding P-chiral phosphine oxides ArPyP(O)R (Py = 2-pyridyl), which were converted into aryl and alkyl derivatives ArR1P(O)R by reaction with Grignard reagents R1MgX with minor loss of enantiopurity. The catalytic asym. synthesis of P-chiral phosphorus compounds is an important way to construct P-chiral ligands. Herein, we report a new strategy that adopts the pyridinyl moiety as the coordinating group in the cobalt-catalyzed asym. nucleophilic addition/alkylation of secondary phosphine oxides. A series of tertiary phosphine oxides were generated with up to 99% yield and 99.5% ee, and with broad functional-group tolerance. Mechanistic studies reveal that (R)-secondary phosphine oxides preferentially interact with the cobalt catalysts to produce P-stereogenic compounds
Recommanded Product: 2-Bromo-6-methylpyridine, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.