Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Name: 2-Amino-5-methylpyridine.
Yadav, Ravi Kant;Sharma, Richa;Gautam, Deepak;Joshi, Jyoti;Chaudhary, Sandeep research published 《 Lewis Acid/Oxidant as Rapid Regioselective Halogenating Reagent System for Direct Halogenation of Fused Bi-/Tri-cyclic Hetero-Aromatic Congeners viaC(sp2) -H bond Functionalization》, the research content is summarized as follows. Herein, the identification of new and fast halogenating reagent system consisting of Lewis acid AlX3 [X=Cl, Br, I] as a halogen source in the presence of tert-Bu hydroperoxide (TBHP) which was utilized for the direct regioselective halogenation on various fused bi-/tri-cyclic hetero-aromatic congeners I [R1 = H; R2 = H, 6-Cl, 6-Me, etc.; R3 = H, 2,4-di-Cl, 4-Ph, etc.], II [R4 = H; R5 = H, 4-Cl, 3-OMe, etc.], caffeine and quinoline viaC(sp2) -H bond functionalization was reported. The operationally simple protocol was quite fast and does not require the external halogenation source at 110°C in 20-60 min and furnished halogenated fused heterocycles I [R1 = Cl, Br, I; R2 = H, 6-Cl, 6-Me, etc.; R3 = H, 2,4-di-Cl, 4-Ph, etc.], II [R4 = Cl, Br, I; R5 = H, 4-Cl, 3-OMe, etc.], 8-chlorocaffeine, haloquinolines in up to 96% yields. The gram-scale synthesis, wide substrate scope, functional group tolerance, control experiments and application to further derivatization/functionalization for C-C bond formation further highlights the versatility of the developed methodol. as well as the compatibility of the new catalyst. The combination of Lewis acid (AlX3) as a halogen source and TBHP (oxidant) as a halogenating reagent system was the first account for the direct regioselective halogenation of several fused bi-/tri-cyclic hetero-aromatic congenersviaC(sp2) -H bond functionalization.
Name: 2-Amino-5-methylpyridine, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.