On November 27, 2008, Soll, Mark David; Le Hir De Fallois, Loic Patrick; Huber, Scot Kevin; Lee, Hyoung Ik; Wilkinson, Douglas Edward; Jacobs, Robert Toms published a patent.Recommanded Product: 1086838-13-2 The title of the patent was Preparation of aryl-fused triazole and pyrazole derivatives and their use as antiparasitic agents against endo- and ectoparasites. And the patent contained the following:
Title compounds I [P = CR1 or N; Q = CR2 or N; V = CR8 or N; W = CR9 or N; X = CR10 or N; Y = CR11 or N; R1, R2, R8, R9, R10 and R11 independently = H, NH2, amido, CN, NO2, halo. etc.; R3, R4 and R5 independently = H, halo, alkyl, hydroxyalkyl, alkylthioalkyl, etc.; R4 and R5 together with the carbon to which they are attached formed a cycloalkyl ring; R6 = H, alkyl, alkoxyalkyl, alkylcarbonyl, alkylthiocarbonyl or (un)substituted benzyl; R7 = H, alkyl, alkoxyalkyl, alkylcarbonyl, alkylthiocarbonyl or (un)substituted phenyl; Z = direct bond, CO, CS or S(O)p; m = 1-3; p = 0-2], and pesticidally acceptable salts, are prepared Thus, e.g., II was prepared by amidation of 4-trifluoromethoxybenzoyl chloride with 2-amino-2-methyl-3-(4,5,7-trichloro-2H-benzotriazol-2-yl)propionitrile which was prepared starting from 4,5,7-trichloro-1H-benzotriazole in a multi-step. I are antiparasitic agents, e.g., II gave at least 90% motility inhibition against Haemonchus contortus at a test concentration of 0.0025 ppm at the 4 days assessment. Therefore, I and pesticidal compositions are particularly useful for controlling endo- and ectoparasites which parasitize animals. The experimental process involved the reaction of 5-Chloro-3-nitropicolinaldehyde(cas: 1086838-13-2).Recommanded Product: 1086838-13-2
The Article related to benzotriazole cyanoethylamino preparation antiparasitic endoparasite ectoparasite, indazole cyanoethylamino preparation parasiticidal infection, endoparasite ectoparasite pesticidal pyrazolopyridine cyanoethylamino preparation and other aspects.Recommanded Product: 1086838-13-2