On January 20, 1989, Corey, E. J.; Posner, Gary H.; Atkinson, Richard F.; Wingard, Astrid K.; Halloran, Daniel J.; Radzik, Donna M.; Nash, John J. published an article.Safety of Pyridine-3-sulfonic acid The title of the article was Formation of olefins via pyrolysis of sulfonate esters. And the article contained the following:
Esters, e.g., I and II, of 8-quinolinesulfonic acid and 2-pyridinesulfonic acid were synthesized from alcs. and the acid chlorides. The secondary esters decomposed cleanly at moderate temperatures to give olefins in high yields. Thus, I was heated at 150° to give 92% cyclohexene. Product studies were consistent with carbocation formation and abstraction by a ring nitrogen to give the olefin. The importance of a basic group was confirmed by pyrolysis of a series of para-substituted cyclohexyl benzenesulfonates III (R = NHAc, NHEt, NO2, Br, Me, MeO, Me2N). Thermolysis of III (R = NHEt, NHAc) cleanly gave cyclohexene in good yield; however, thermolysis of III (R = NO2, Br, Me Me) gave cyclohexene in low yield along with considerable amounts of tar. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Safety of Pyridine-3-sulfonic acid
The Article related to olefin preparation sulfonate pyrolysis, pyrolysis sulfonate ester, alkyl quinolinesulfonate preparation thermolysis, pyridinesulfonate preparation thermolysis, thermal elimination alkyl quinolinesulfonate and other aspects.Safety of Pyridine-3-sulfonic acid