On March 12, 1998, Daines, Robert A. published a patent.Name: N,3-Dimethylpyridin-2-amine The title of the patent was Preparation of 3,4-dinitrobenzamides as calcitonin gene related peptide receptor ligands.. And the patent contained the following:
Title compounds [I; R1 = H, Me, alkyl, phenylalkyl, heterocyclylalkyl, aminoalkyl, carboxyalkyl, alkoxycarbonylalkyl, etc.; R2 = (substituted) aryl, heteroaryl, arylalkyl, heteroarylalkyl; R1R2N = (benzo-fused) 5-6 membered heterocyclyl], were prepared Thus, N-methylaniline in CH2Cl2 was treated with Et3N and then with 3,4-dinitrobenzoyl chloride and the mixture was shaken overnight to give N-methyl-N-phenyl-3,4-dinitrobenzamide. I antagonized CGRP receptors with IC50 = 0.001-100 μM. The experimental process involved the reaction of N,3-Dimethylpyridin-2-amine(cas: 156267-13-9).Name: N,3-Dimethylpyridin-2-amine
The Article related to nitrobenzamide preparation cgrp related disease treatment, calcitonin gene related peptide antagonist dinitrobenzamide, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Name: N,3-Dimethylpyridin-2-amine