On October 1, 2013, Zhao, Hong-Wu; Yue, Yuan-Yuan; Li, Hai-Long; Song, Xiu-Qing; Sheng, Zhi-Hui; Yang, Zhao; Meng, Wei; Yang, Ze published an article.Synthetic Route of 75449-26-2 The title of the article was Novel axially unfixed biaryl-based water-compatible organocatalysts: design, synthesis and their asymmetric catalysis in direct aldol reactions in water. And the article contained the following:
A family of novel axially unfixed biaryl-based, water-compatible bifunctional organocatalysts I [R = 4-MeC6H4, 4-MeC6H4, 1-naphthyl; X = CH, N] were designed and synthesized for asym. catalytic direct aldol reactions in water. These organocatalysts are comprised of prolinamide, aromatic sulfonamide and biaryl motifs. Under the optimal reaction conditions, one organocatalyst in particular delivered excellent stereocontrol (up to 99% ee and 99:1 dr) in direct aldol reactions of cyclohexanone with a variety of aromatic aldehydes in water. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Synthetic Route of 75449-26-2
The Article related to asym aldol addition biaryl catalyst preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Synthetic Route of 75449-26-2