On December 7, 2003, Tabanella, Stefania; Valancogne, Ingrid; Jackson, Richard F. W. published an article.Application In Synthesis of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid The title of the article was Preparation of enantiomerically pure pyridyl amino acids from serine. And the article contained the following:
A range of substituted pyridyl amino acids have been prepared by palladium catalyzed cross-coupling of serine-derived organozinc reagents with differently substituted halopyridines. Following this procedure a DMAP analog has been synthesized and used as a building block in the preparation of two related tripeptides, which have been tested as catalysts in the kinetic resolution of trans-2-(N-acetylamino)cyclohexan-1-ol, resulting in modest enantioselectivity. The experimental process involved the reaction of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid(cas: 282734-37-6).Application In Synthesis of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid
The Article related to pyridyl amino acid preparation cross coupling organozinc serine, kinetic resolution catalyst pyridyl amino acid, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Application In Synthesis of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid