On August 31, 2011, Mehul, Dave; Senthil, A.; Hardik, Thakkar R.; Ravikumar; Tejas, Lad published an article.SDS of cas: 132-20-7 The title of the article was Formulation and evaluation of orodispersible tablets of pheniramine maleate. And the article contained the following:
Orodispersible tablets of pheniramine maleate were prepared by direct compression method using three super disintegrants, viz., croscarmellose sodium, crospovidone and sodium starch glycolate at different concentrations with microcrystalline cellulose were used along with sodium bicarbonate and citric acid as effervescent agent. Orodispersible tablet is the fast growing and highly accepted drug delivery system, convenience of self administration, compactness and easy manufacturing Pheniramine maleate is a member of alkylamine class of H1 receptor antagonists. It is an antihistamine used in the treatment of allergic conditions including urticaria and angioedema. It is completely absorb after oral administration. The bland were examined for angle of repose, bulk d., tapped d., compressibility index and hausner’s ratio. The prepared tablets were evaluated for thickness, hardness, friability, and weight variation, content uniformity, wetting time, Water absorption ratio, in-vitro dispersion time, dissolution studies and FTIR studies. Twelve formulations F1 to F12 were prepared with three super disintegrants with different concentration The optimum formulation was chosen and their optimum results were found to be in close agreement with exptl. finding. Among three super disintegrants crospovidone F5 emerged as overall best formulation. Short-term stability studies on the formulations indicated no significant changes in the drug content and in vitro dispersion time (p < 0.05). The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).SDS of cas: 132-20-7
The Article related to pheniramine maleate orodispersible tablet formulation superdisintegrant, Pharmaceuticals: Formulation and Compounding and other aspects.SDS of cas: 132-20-7