Related Products of 128071-75-0In 2020 ,《Selective Insertion of Alkynes into C-C σ Bonds of Indolin-2-ones: Transition-Metal-Free Ring Expansion Reactions to Seven-Membered-Ring Benzolactams or Chromone Derivatives》 was published in Organic Letters. The article was written by Wang, Mengdan; Yang, Yajie; Song, Bo; Yin, Liqiang; Yan, Shuhui; Li, Yanzhong. The article contains the following contents:
An unprecedented ring expansion reaction of indolin-2-ones with alkynyl ketones under transition-metal-free conditions has been developed. Base-promoted selective cleavage of a C-C σ bond of the amide is the key in this process, which provides a straightforward and efficient way to synthesize seven-membered-ring benzolactams or chromone derivatives The significant advantages of this method include readily accessible starting materials, wide scope and functional group tolerance, and high atom economy. In the experimental materials used by the author, we found 2-Bromonicotinaldehyde(cas: 128071-75-0Related Products of 128071-75-0)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Related Products of 128071-75-0