Name: 5-Bromo-2-chloropyridineIn 2017 ,《Sequential one pot double C-H heteroarylation of thiophene using bromopyridines to synthesize unsymmetrical 2,5-bipyridylthiophenes》 was published in Tetrahedron. The article was written by Kieffer, Charline; Babin, Victor; Jouanne, Marie; Slimani, Ikram; Berhault, Yohann; Legay, Remi; Sopkova-de Oliveira Santos, Jana; Rault, Sylvain; Voisin-Chiret, Anne Sophie. The article contains the following contents:
We present C-H heteroarylation reactions between thiophene and variously substituted bromopyridines. The objective was to synthesize unsym. 2,5-bipyridylthiophenes. We studied the reaction conditions allowing to a sequential one-pot double C-H heteroarylation, in a view to introduce two different pyridyl moieties at positions 2 and 5 of the thiophene ring using bromopyridines. 11 original unsym. 2,5-bipyridylthiophenes were synthesized and characterized, including 2,5-di(pyridin-2-yl)thiophenes for which the preparation by classical cross-coupling reactions is challenging. Finally, with the addnl. synthesis of both an unsym. 2,5-biarylthiophene and an original pyrimidin-thiophene-furan scaffold, we shown that our methodol. was also an efficient tool to access to new heterocyclic sequences. In the part of experimental materials, we found many familiar compounds, such as 5-Bromo-2-chloropyridine(cas: 53939-30-3Name: 5-Bromo-2-chloropyridine)
5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Name: 5-Bromo-2-chloropyridine