《Enantioselective Synthesis of 4-Cyanotetrahydroquinolines via Ni-Catalyzed Hydrocyanation of 1,2-Dihydroquinolines》 was published in Organic Letters in 2020. These research results belong to Jiao, Mingdong; Gao, Jihui; Fang, Xianjie. HPLC of Formula: 197958-29-5 The article mentions the following:
A Ni-catalyzed asym. hydrocyanation that enables the formation of 4-cyanotetrahydroquinolines in good yields with excellent enantioselectivities is presented herein. A variety of functional groups are well-tolerated, and a gram-scale reaction supports the synthetic potential of the transformation. Addnl., several crucial intermediates for pharmaceutically active agents, including a PGD2 receptor antagonist, are now accessible through asym. synthesis using this new protocol. In the part of experimental materials, we found many familiar compounds, such as 2-Pyridinylboronic acid(cas: 197958-29-5HPLC of Formula: 197958-29-5)
2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. HPLC of Formula: 197958-29-5