The author of ãPalladium-Catalyzed Electrochemical C-H Alkylation of Arenesã?were Yang, Qi-Liang; Li, Chuan-Zeng; Zhang, Liang-Wei; Li, Yu-Yan; Tong, Xiaofeng; Wu, Xin-Yan; Mei, Tian-Sheng. And the article was published in Organometallics in 2019. Related Products of 3510-66-5 The author mentioned the following in the article:
2-Arylpyridines were electrochem. ortho-alkylated by RBF3K, the reaction being performed in undivided cell in aqueous solutions catalyzed by Pd(OAc)2. Palladium-catalyzed electrochem. C-H functionalization reactions have emerged as attractive tools for organic synthesis. This process offers an alternative to conventional methods that require harsh chem. oxidants. However, this electrolysis requires divided cells to avoid catalyst deactivation by cathodic reduction Herein, we report the first example of palladium-catalyzed electrochem. C-H alkylation of arenes using undivided electrochem. cells in water, thereby providing a practical solution for the introduction of alkyl group into arenes. The experimental process involved the reaction of 2-Bromo-5-methylpyridine(cas: 3510-66-5Related Products of 3510-66-5)
2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Related Products of 3510-66-5