Raji Reddy, Chada; Bodasu, Srinivas; Mallesh, Kathe; Prapurna, Y. Lakshmi published an article in 2021. The article was titled ãSynthesis of Fused Pyrimido[1,6-a]indolones via Rhodium(III)-Catalyzed Cascade Annulationsã? and you may find the article in Synthesis.Related Products of 128071-75-0 The information in the text is summarized as follows:
A novel method for the synthesis of fused pyrimido[1,6-a]-indolone derivatives, e.g., I by annulation of 2-alkynylaryl aldehydes/2-alkynylarylidene ketones with N-(pivaloyloxy)-1H-indole-1-carboxamide catalyzed by rhodium has been accomplished. The reaction proceeds through C-H activation based annulation with alkyne moiety followed by addition of nitrogen on to aldehyde/activated alkene to give the products in moderate to good yields. Highly fluorescent dipyrrinone analogs could be synthesized from the derived products. The experimental process involved the reaction of 2-Bromonicotinaldehyde(cas: 128071-75-0Related Products of 128071-75-0)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Related Products of 128071-75-0