Chen, Xiaoxi; Fan, Shuai; Zhang, Meng; Gao, Yuzhen; Li, Shangda; Li, Gang published their research in Chemical Science in 2021. The article was titled ãPalladium-catalyzed remote para-C-H activation of arenes assisted by a recyclable pyridine-based templateã?Name: Pyridin-3-ylboronic acid The article contains the following contents:
An unprecedented pyridine-based para-directing template (DT) assisted, Pd-catalyzed para-C-H alkenylation of three classes of arenes, i.e. phenylpropanoic acids, 2-Ph benzoic acids and benzyl alcs., with a series of alkenes included perfluoroalkenes was reported. Notably, the pyridine-based para-DT could be easily synthesized and readily recycled under mild conditions. These results may find application in rapid construction of para-substituted arenes and stimulated the exploration of novel methods for para-C-H functionalization of arenes. In the part of experimental materials, we found many familiar compounds, such as Pyridin-3-ylboronic acid(cas: 1692-25-7Name: Pyridin-3-ylboronic acid)
Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Name: Pyridin-3-ylboronic acid