ãRapid Access to Diverse Potassium Acyltrifluoroborates (KATs) through Late-Stage Chemoselective Cross-Coupling Reactionsã?was written by Deng, Xingwang; Zhou, Guan; Han, Xiao; Ullah, Khadim; Srinivasan, Rajavel. Computed Properties of C5H3Br2N And the article was included in Organic Letters in 2021. The article conveys some information:
Functionalization of acyltrifluoroborates K[BrArCOBF3] (Ar = arylene, 2,5-thiophenediyl) was achieved by late-stage cross-coupling with arylboronic acids, arylacetylenes and aromatic amines, providing access to substituted trifluoroborates K[RArCOBF3] (R = aryl, alkynyl, arylamino). Potassium acyltrifluoroborates (KATs) are opening up new avenues in chem. biol., materials science, and synthetic organic chem. due to their intriguing reactivities. However, the synthesis of these compounds remains mostly complicated and time-consuming. Herein, we have developed chemoselective Pd-catalyzed approaches for the late-stage diversification of arenes bearing prefunctionalized KATs. These approaches feature chemoselective cross-coupling, rapid diversification, functional group tolerance, mild reaction conditions, simple operation, and high yields. In the experimental materials used by the author, we found 2,5-Dibromopyridine(cas: 624-28-2Computed Properties of C5H3Br2N)
2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Computed Properties of C5H3Br2N