SDS of cas: 3510-66-5In 2019 ,ãPalladium-Catalyzed Hydrocarbonylative Cyclization Enabled by Formal Insertion of Aromatic C=N Bonds into Pd-Acyl Bondsã?appeared in Organic Letters. The author of the article were Zhou, Xibing; Chen, Anrong; Du, Wei; Wang, Yawen; Peng, Yu; Huang, Hanmin. The article conveys some information:
An efficient new formal insertion strategy via combination of reductive elimination and oxidative addition sequence was reported, in which the transient N-acyliminium ions formed via hydrocarbonylation function as key intermediates. This strategy has enabled a novel palladium-catalyzed hydrocarbonylative cyclization of azaarene-tethered alkenes or dienes via sequential insertion of a C=C bond, CO, and a C=N bond into palladium-hydride bonds. This method provides a new and highly efficient synthetic approach to quinolizinones and its derivatives with extended π-conjugated systems, possessing tunable emission wavelengths and good photoluminescence capabilities.2-Bromo-5-methylpyridine(cas: 3510-66-5SDS of cas: 3510-66-5) was used in this study.
2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. SDS of cas: 3510-66-5