The author of 《Fluorescent probes for detecting glutathione: Bio-imaging and two reaction mechanisms》 were Xia, Ying; Zhang, Huihui; Zhu, Xiaojiao; Fang, Min; Yang, Mingdi; Zhang, Qiong; Li, Xiaowu; Zhou, Hongping; Yang, Xingyuan; Tian, Yupeng. And the article was published in Dyes and Pigments in 2019. Product Details of 31106-82-8 The author mentioned the following in the article:
A series of compounds (W1-W8) based on triphenylamine with -C=N- or -NH- group, were designed and studied by fluorescence emission spectra and DFT/TDDFT calculations Probes W1-W4 were selectively leveraged to sensitively detect glutathione by two distinct reaction mechanisms, thereinto, W1-W2 featured a convenient detection for glutathione using hydrolysis and W3-W4 utilized displacement to probe glutathione possessing sensitivity and practicability. Compound W5-W8 here provided an avenue for understanding structure-property relationship. Taken considerations for toxicity and biocompatibility together, W1-W4 showed great advance for endogenously and exogenously imaging GSH in living cells. After reading the article, we found that the author used 2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Product Details of 31106-82-8)
2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Product Details of 31106-82-8