《Electroreductive 4-Pyridylation of Electron-deficient Alkenes with Assistance of Ni(acac)2》 was written by Zhang, Sheng; Li, Lijun; Li, Xinru; Zhang, Junqi; Xu, Kun; Li, Guigen; Findlater, Michael. Electric Literature of C6H4N2 And the article was included in Organic Letters in 2020. The article conveys some information:
An electroreductive 4-pyridylation of activated alkenes was developed in an undivided cell with the assistance of Ni(acac)2 (acac = acetylacetone). This novel protocol was compatible with a broad range of electron-poor alkenes, which were commonly regarded as challenging substrates in the previous conventional approaches. Moreover, a series of cyclic voltammetric experiments were conducted to reveal the unique role of Ni(acac)2 differentiating reduction process of reaction partners. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1Electric Literature of C6H4N2)
4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Electric Literature of C6H4N2