《Synthesis of α-Heteroaryl Propionic Esters by Palladium-Catalyzed α-Heteroarylation of Silyl Ketene Acetals》 was written by Li, Bowen; Luo, Bangke; Blakemore, Caroline A.; Smith, Aaron C.; Widlicka, Daniel W.; Berritt, Simon; Tang, Wenjun. Recommanded Product: Methyl 5-bromopicolinateThis research focused ontrimethylsiloxy propene tertiary butoxy heteroaryl bromide palladium catalyst heteroarylation; tertiary butyl pyridinyl propanoate preparation. The article conveys some information:
A practical and efficient synthesis of α-heteroaryl propionic esters was developed by employing palladium-catalyzed α-heteroarylation of silyl ketene acetals, forming a wide variety of α-heteroaryl propionic esters with various substituents and functionalities in high yields. The success of this transformation was credited to the development of the bulky P,P=O ligand. This method provided an efficient synthesis of α-heteroaryl propionic acids. In the experiment, the researchers used many compounds, for example, Methyl 5-bromopicolinate(cas: 29682-15-3Recommanded Product: Methyl 5-bromopicolinate)
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