《Intramolecular electrochemical dehydrogenative N-N bond formation for the synthesis of 1,2,4-triazolo[1,5-a]pyridines》 was written by Li, Yong; Ye, Zenghui; Chen, Na; Chen, Zhenkun; Zhang, Fengzhi. Formula: C6H4N2This research focused ontriazolopyridine preparation green chem; amidine pyridyl electrochem dehydrogenation. The article conveys some information:
A metal- and oxidant-free intramol. dehydrogenative N-N bond formation has been developed under mild and scalable electrolytic conditions. Various valuable 1,2,4-triazolo[1,5-a]pyridines I (R1 = t-Bu, cyclopropyl, 2,6-dichlorophenyl, 2-naphthyl, pyridin-4-yl, etc.; R2 = H, Me; R3 = H, Me, Et, F, Cl, 4-methylphenyl, 2-thiophenyl; R4 = H, Me, MeO; R5 = H, Me, Cl; R3R4 = CH=CH-CH=CH) were synthesized efficiently from the readily available N-(2-pyridyl)amidines II. The reactions were conducted in a simple undivided cell under constant current conditions with n-Bu4NBr as both the redox mediator and the electrolyte. This protocol was applied to the efficient synthesis of key intermediates for anti-diabetic compounds After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Formula: C6H4N2)
4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Formula: C6H4N2